In 1956, Meyer and others first began to study the types and contents of acid mucopolysaccharides in different tissues, and identified that there were Chondroitin sulfate powder, hyaluronic acid, keratin sulfate and other mucopolysaccharides in connective tissue.
chemical property
Unsaturated sugars generated by CS under acidic, alkaline, and enzymatic conditions, including low molecular weight CS and CS oligosaccharides or disaccharides, are related to β- Elimination reaction.
The degradation degree of CS under acidic, alkaline, and neutral conditions is represented by the UV absorbance value at 232nm. The higher the UV absorbance value, the greater the degradation degree, reflecting the stability of CS under different conditions.
physical property
CS is an acidic mucopolysaccharide substance extracted and prepared from animal tissues, which is a white or almost white powder; Odorless; It has hygroscopicity. The aqueous solution of this product is viscous and does not coagulate when heated. This product is easily soluble in water and insoluble in organic solvents such as ethanol, acetone, and ether. Its salts are relatively stable to heat and are not damaged when heated up to 80 ℃. Chondroitin sulfate aqueous solution is unstable when exposed to high temperature or acid. It is mainly deacetylated or degraded into monosaccharide or polysaccharide with small molecular weight.
